Aarhus

Principal investigator:
Dr Karen Østergaard

Aarhus Kummunehospital
Department of Neurology
Norrebrogade 44
DK-8000 Aarhus C


Expertise of the participating organization:

The Aarhus group members have for many years been involved in research into neurodegenerative diseases and movement disorders. The "Neuro-center" of Aarhus, apart from clinical neurology includes, departments of neurosurgery (center of STN-deep brain stimulation), neuropathology, neuroradiology,(MRI-Centres), neurophysiology and a PET-center directed by Professor Albert Gjedde.Since 1980 Prof. Dr. Erik Dupont MD has been responsible for the Parkinson's disease clinic and other movement disorders at The Dept. of Neurology, Aarhus University Hospital and has participated in numerous international drug trials in PD.


Recent publications relevant to the EMSA-SG:

Rasmussen VG, Poulsen SH, Dupont E, Ostergaard K, Safikhany G, Egeblad H. Heart valve disease associated with treatment with ergot-derived dopamine agonists: a clinical and echocardiographic study of patients with Parkinson's disease. J Intern Med 2008; 263: 90-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18036161

Hertz JM, Ostergaard K, Juncker I, Pedersen S, Romstad A, Moller LB, et al. Low frequency of Parkin, Tyrosine Hydroxylase, and GTP Cyclohydrolase I gene mutations in a Danish population of early-onset Parkinson's Disease. Eur J Neurol 2006; 13: 385-90. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16643317

Hjort N, Ostergaard K, Dupont E. Improvement of sleep quality in patients with advanced Parkinson's disease treated with deep brain stimulation of the subthalamic nucleus. Mov Disord 2004; 19: 196-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14978676

Vafaee MS, K OS, Sunde N, Gjedde A, Dupont E, Cumming P. Focal changes of oxygen consumption in cerebral cortex of patients with Parkinson's disease during subthalamic stimulation. Neuroimage 2004; 22: 966-74. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15193628

Romstad A, Dupont E, Krag-Olsen B, Ostergaard K, Guldberg P, Guttler F. Dopa-responsive dystonia and Tourette syndrome in a large Danish family. Arch Neurol 2003; 60: 618-22. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12707079