Cure MSA

Country specific patient information

Santander

Principal investigator:

Prof. Jose Berciano

University Hospital Marqués de Valdecilla
University Hospital
E-39008 Santander
neuro(at)humv.es

Expertise of the participating organization:

The Santander group has been actively involved in MSA research since 1975; in fact, the prevalent ratio of degenerative ataxias including MSA in Cantabria, Spain, is one of the highest in the world.

Recent publications relevant to the EMSA-SG:
 

Infante J, Garcia-Gorostiaga I, Sanchez-Juan P, Sanchez-Quintana C, Gurpegui JL, Rodriguez-Rodriguez E, et al. Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach. Eur J Neurol 2008; 15: 431-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18284424

 

Berciano J, Boesch S, Perez-Ramos JM, Wenning GK. Olivopontocerebellar atrophy: toward a better nosological definition. Mov Disord 2006; 21: 1607-13. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16874757

 

Berciano J, Infante J, Garcia A, Polo JM, Volpini V, Combarros O. Very late-onset Friedreich's ataxia with minimal GAA1 expansion mimicking multiple system atrophy of cerebellar type. Mov Disord 2005; 20: 1643-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16092110

 

Berciano J, Wenning GK. The Lewis family revisited: no evidence for autosomal dominant multiple system atrophy. Parkinsonism Relat Disord 2005; 11: 363-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16103001

 

Infante J, Llorca J, Berciano J, Combarros O. Interleukin-8, intercellular adhesion molecule-1 and tumour necrosis factor-alpha gene polymorphisms and the risk for multiple system atrophy. J Neurol Sci 2005; 228: 11-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15607204

 

Combarros O, Infante J, Llorca J, Berciano J. Genetic association of CYP46 and risk for Alzheimer's disease. Dement Geriatr Cogn Disord 2004; 18: 257-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15286456

 

Combarros O, Infante J, Llorca J, Berciano J. Interleukin-1A (-889) genetic polymorphism increases the risk of multiple system atrophy. Mov Disord 2003; 18: 1385-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14639688

 

Berciano J, Valldeoriola F, Ferrer I, Rumia J, Pascual J, Marin C, et al. Presynaptic parkinsonism in multiple system atrophy mimicking Parkinson's disease: a clinicopathological case study. Mov Disord 2002; 17: 812-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12210882